USMLE Step 1 – How To Study For Biochemistry

I have been getting lots of emails recently from students asking me how should they study biochemistry. Let me tell you something.

usmle step 1 biochemistry

Biochemistry is one of the toughest and most important sections of the exam. If your biochemistry is weak don’t even go for the exam. I got emails from students who were strong in everything except biochemistry and failed the exam. So you better take it seriously and prepare strong!

Listen, the rule is if you are weak on any subject you should focus on that more. I was really weak in biochemistry when I came out of the medical school. Our biochemistry professor did not teach much. So I knew I had to learn it from the beginning.

So when I started to prepare for Step 1, the first subject I wanted to master was biochemistry. I bought these Kaplan Lecture Notes Biochemistry and Medical Genetics and I had the Kaplan videos. I watched all the videos and read the corresponding section of the lecture note. Both the Kaplan videos and lecture note were amazing. They are the reason why my biochemistry is super strong and I scored 266 on Step 1.

It took me about 3 weeks to go over all the biochemistry Kaplan videos and the lecture note once. I am never satisfied with one read. So I read the entire biochemistry lecture note all over again. After my second read, I knew I am good in biochemistry now. However, I wanted to read more and get stronger. So I read the entire first aid’s biochemistry section and it took me a week.

Once I was done with Kaplan & First Aid I started with UW’s biochemistry question. And believe me, I was flying through them. There were definitely some weird questions on the UW but I took notes on them on my First Aid.

Important things to remember when it comes to biochemistry:

Many students get scared when it comes to pathways. Let me tell you something, you don’t need to memorize the pathways at all. You just need to understand them but memorize the diseases on the pathways.

Make sure you know where each pathway takes place, which enzyme is the rate limiting enzyme and deficiency of which enzyme leads to which disease.

I also want you to be able to teach someone the pathways by looking at the pathways. If you can teach someone the pathways that mean you know them really well!

Next, let’s talk about the molecular biology section of the biochemistry. It is a very high yield section and exam loves it! When you study molecular biology section make sure you know everything about DNA, DNA replication, transcription, translation, and mutations.

When it comes to vitamins make sure you memorize everything about vitamins. On my exam, I had 5 to 7 question straight from the vitamin section of First Aid.

That’s all it is for biochemistry. If you still need my help and want me to make you a good study schedule feel free to check out my consulting service.

Resources I used for my Step 1 biochemistry preparation to get 266: